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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a8cce1fcb328d05ff609d89ca9eb9765241eef5326438774c1636990db097f7' 
  AND token = 'U4C7UKI7zCCFFunVit7y3ibVpySuszWTPznyTSd89Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}