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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b515a55dda8700b63b21c0bdc2f1b57c00192acc35cf2c9d8500e9cbafc0de0' 
  AND token = '1+28a6rQHhGZFdRn3A8OFp4egY09Gw4BSNMoRk2q69Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}