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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b276101dc205a090f3949cf357b5e49e5c1ee37caf7c48c50d03846e9d87e7' 
  AND token = 'T+Xx1+sMN7hby4SP8ZOe8Ke2SsvvW5DKPu/bui8yWtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}