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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86250964c151742cb3b691b5451412ba8ea3912fc87e21b282f766776662ac76' 
  AND token = 'qusK/+wOMrFDd3hj+zvfoF6n7iDg66r97/Psa0HpFZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}