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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4bf74c2f1fafeb3e9c41abf207205249e2064d315b95aaa00302882cfa02fbe' 
  AND token = 'L5SxQ1+MzqTc44JpCLsEEwiUzRj48LWcqQu7xxTXh1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}