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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e5260e2e4f011f611cb6096dbbf78e7e45c09c516a71eeea363e4c6519e5e88' 
  AND token = 'rXlt/l9IycaWnaDN+yxcEwu417PAfjAT3uWxvk7cSOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}