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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16100d23a51bb1599e281d08e9137f89e4870d5487b950724205e2b0395c1ea0' 
  AND token = '1p0nmBWIAhzT4sFLZDYYLUmOQnQfZ6sHDK/V/VWFdlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}