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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d8fb7ffdd10e2daaefc491dc786f720fbab0227f6e1a3433403438deb808f7' 
  AND token = 'u0xjkMKdcIA4lbfHgfIeKw88ZOiTjfQNhMK5NcXAXA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}