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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e830189271cee18d2c75064702a994c199a17305dbe240249b97d0910064fc31' 
  AND token = 'BEd0B4mzKqTUO2t/AkxLColOtbynJ9htPXajWkH3sLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}