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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f243ad2c938b3ecdc3f21a17ff1e18e63acfc11d3f1f88d686216fe5879aacdf' 
  AND token = 'bX/NXqQTof6UGOLK5HqV6ERWQScjancYiLWyVTO0ssk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}