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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa78debc5f42883ca67a3ba9cf1c3e5acc560264af2d53f63b68b8ae04b06228' 
  AND token = 'aO0qyehPZLcZ6p+vYFM35pWTb//w7eQSYBqENKqSVSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}