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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a47a7b6bc220a83ee615c78dac619a0ade5f4b9585bc2598a092070c20ee555d' 
  AND token = 'ax7a3BE/nrTsmqdpQ8cWnSR1UsssAEaaQTRjcxNFhpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}