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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dff8fca86a8a1f49cec0fe806b1ca06df60cd3620e34dbe832c43e96e1e9cdd' 
  AND token = 'AnRhWAg17dqtByRWee0m4sO4uD34TLINV47pxUFhZqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}