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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0099c2131ec818f491881856de4a72d98db09920d7c10962a75e9a9b04e08a79' 
  AND token = 'IjTXtLnQ/Fq47gCgs6WCQGuFUdiV6nqbs3GTooJHuhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}