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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6850590b15465c7db307a0198251e6694aa3983ddab0ff9de8c8ed16e4d3736' 
  AND token = 'JC3+t6AOQxS/McNJ+a82PiR2UGqPN3VDeL/QNLE89dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}