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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654e1c700a11fd2dee4deada4f38550345078b43472df09b74335e6382ba4693' 
  AND token = 'r8tT8EXfWg6c6tlNDc/QlIU44GuctmL/UJZBiqeQ9zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}