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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0c11f7284d4fa0d7fb0c9a7375c5861a1a5d962f5f78f0d8b12dbaa5884e36' 
  AND token = '9gDVvGUdqMm3kiINN04jisb1bMoUW0G5nrU+dAwIo7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}