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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf07ddff8a0eac3ec15b5682d3f5b129f7be8ac6682de95fbbd0f287750cdc0' 
  AND token = 'IlKjaEDa15xhpNl6iqozrypBhL5624gbHxQQAMY+4ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}