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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'add2ceb0e67a209ecc0c8e997b1b3415905f1298aa5da79d050362dc7efc4c8f' 
  AND token = 'C9m9P1GHnGkPeLNiuw7sD5mMyTw5IpWZ6WND9T9/mPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}