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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef353d36e5c5a9482df649a2e03d79bf358ac105e5239365557715a362bda657' 
  AND token = 'v8sZEJSuOMCTMsv+C5fBpwBaDR5adsqVjE5WMCeNkAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}