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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b4dce347ee848b40f9c4e80a4fed37146e1f4365cd6f5a312ac4601fe2f6848' 
  AND token = 'hjDg3xfVfrYOqKUkV7yVMyxcgHuQIGWw7L6Fvb9anCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}