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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f949df242c9376255d8bcbdbd4e2a2d12f3d6e732f71df9db615565d4d8cd0e6' 
  AND token = 'HcWfo9AhMHUd/oeIDb2+hVqhYGlleTb5S2AxG5d/Lkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}