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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d1a60424c2f63bc0652dca88734ba2f102b235e3a601facd403220e5632652' 
  AND token = 'Nn7heQvk+POQ8VdWtLg/hf81ELzHvFwiMt9jTnkFBlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}