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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb294bebb2e8d7cf351ee10a0391500844310ac1818da3cf3c66ddc81ded647' 
  AND token = 'SNPUvMyyRwUPX3zEm1BQ2k7cW6WCcMQwXSk9StUd0wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}