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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fcd1da533b5d2602120e81f6892fc4b2345db729b60c269a55650785a81794d' 
  AND token = 'jDC2Eb5vXxKWwb5eaLVbjAhjfISZjuWyO4eGogF0whM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}