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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ec0ecd610bea3a0204bd6f8febc4a8a32eba21dbd4ca6c485ec4150f7de2b7' 
  AND token = '8Za8wWELWpCsYEVxoj6rDfBH5EoAxUaUKdRWDP80LL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}