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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e58de7293f7881c11fb73982019b017f021aff588acbdc21172f0e55a6a0359' 
  AND token = 'tG9IYBOobVQsUBIjygTu/KKA4y4jLGlBO6BQSfS39ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}