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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24395f5649e56cae1128f6f7c064ee1bd3921243f1beb6b64c7d1bf550213467' 
  AND token = 'E3sG06rLcyhDVITWPXuSRM3L7L4QRHuAflxQrAEbSZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}