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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '148f1c8fb8467c153d8353a3d78c4ff86bb88620e71c74eb0cf0ffd8c6c28a36' 
  AND token = 'hRMsJ5TynqHGl2xWyVcglvHY8FZuc7tUbwLUGOJg4So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}