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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec349824febe238f0aeed6c7b3e9602cc54a0e14e0593529bd81928a796f049' 
  AND token = 'Bz4XnZNeTFVJZQRl9tdBI9bVIjhUUWMtgXbS17PP/Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}