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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a72a582a4a3d814eaca6a48d7f86e31fa766812ed4c42749c45642f431e4f0c' 
  AND token = 'zA51H+m6ckBNapcB2QDFcGMdbMWN7A7GP7kIdeUQTOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}