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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2d0ebbbaa214b947ebd0a8d0e701c4f2f0e819bb687e54f51ff7c7c8d9c444' 
  AND token = '48iPRdRQEhirgwhmjmVxvJV0aamLFiyO0QON9IB1fi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}