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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d350c38b5dd76012e913283026362ad8ac036aa8c39c5a7d332726cb77b736' 
  AND token = '+CvZqm6OnvahgsSH6LZn2DjhlaV009AHeeBqv3sKKms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}