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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666fb3e9c9c1cce9570cc37796b9a1778ff209607a9db757dacca372af3d4b47' 
  AND token = 'EZDQgOGUBgBEx9nBU1/iPYqu+Zs0WlT19sQ2bgv6d50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}