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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29573e84f3f18c123381eb8c81ce376e305da52d2fe510b3aad92bba89401a52' 
  AND token = 'sp+76rSltxyYJjAAVCgdMaVTaE+RAy70PYlPcHmw1RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}