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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9a27fd5c7a1fffb75ab8468a61feca596977feea98f1bccb4ccf93bb2cb7821' 
  AND token = 'j6OoZb6T9EEXY9KFN+KH2fu9SHUQbjVPEoghUF8cnEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}