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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8273dcf405adf08c04bf8a9edc16ad4276f9af00dfc9c6586095c4bbd1f9db59' 
  AND token = 'Yk8t2NgmZs0XfckyjL3B0Z3BTkrLTmwHunJsAUu6GUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}