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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c261bb5b9cf32b6f2f9b4a9bed6c4bb297df1501f2f7bc688029675dff26d9' 
  AND token = 'MNQty32gXIwuUypgZApf+NoaLY8Nb+IBRRJbGYHt3FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}