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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78bfa91e145ff1ad164601813e5e4395ca7a0b885c6f2055768058cdd549ff2' 
  AND token = 'o9j/S4B4LeyGj1e3REmd+DxwZ4WfalUP5g64uyACTR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}