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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59414af9451d03e426be5a0dae80e9eb01c25edef603d223640d25dc8a97e187' 
  AND token = '/nY9uEKEpuVMtvBk9W6GUE980uk+7XiKIEHFaIpPTFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}