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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fa43c6d6eae761cced1bd2a71590f9e2f9df42d114d510000e7e9bc69d9016f' 
  AND token = '5U//oNw0Qu0tcghifbTcYUcvbRRKlDz8s65VxNYBKJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}