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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b29049116cfa650a6f1ea5d02ca79b5c4d808498e715a43c272359aaa07cc0e' 
  AND token = 'j+ERO4Zp8HKC9Nm1XDLPlJlHaz8kp5kLCkf+xe7uDiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}