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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d8fa9378db5a4b00dadc6e5c068e61a9cf14414df928834990f7f591850e6aa' 
  AND token = '7Id8SWPu1dLfalYrIo+Rb1oYcstXdqTEKQe4/6XcNYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}