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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa86ddd873ea012470a237db00b0f85f1677bcc8b689997069d647e255b8024' 
  AND token = 'Zm8KE9+oEteWpB9xK6eIsLkosi4ePF2to9BD1rxlJmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}