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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6783f40ac3139c3e6ad727e5c04e4111311750a605915c7de1dc06ca2be4fc' 
  AND token = 'RxIVL6fo12BTPn5HVISSllKC0Bd1LSl7gRsEz/CDm4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}