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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66cbdbef61c12aa9d9eb987d431d12de0be9bd8b3ca6969ee317f344ff31f09c' 
  AND token = 'DPqn3nEyrs3pp95wsgBvZkHKNSutpahfPMbNA23ge7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}