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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2603e08c2214838f14078838df6c378a99a367e33bad08d6d3a3db4b3e58abf5' 
  AND token = '+bSFUtFtQQKesFRuox1qCaxMQFm+jtyFnms1RxokPZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}