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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5388bc539973489670dfafb42b372704f36d23dc2b78f6cbc5f5c9ee00c69ff' 
  AND token = 'ZZOTC+VI8Od2iv61+hnX1jqb+WwbewBl2Nt3Rko2CRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}