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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f101504aa1a0d8525a7d45e6e7b1060db9752e79c34285ed720145e95c5f45ff' 
  AND token = '58r2ZqQMp4nAyxs2YrlhkEEW6QGyUOfYzWJt+DoQTno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}