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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0b45b23be05e673730d552996b9f875d06e1c04c85a48d619cb0218ca7257bc' 
  AND token = 'tTFT+zSy3jxfe1822u0kKeJUJfr3yT7B0tYJWgq+TXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}